임경태 연구실

Understanding epigenetic mechanisms underlying alveolar differentiation from early lung progenitor cells using single cell technology, transcriptome, chromatic accessibility assays, and advanced technologies like 3D genomics and spatial transcriptomics.

Investigating human alveolar type 2 (AT2) cells' production and assembly of surfactant proteins, their self-renewal capacity, and regeneration of AT1 cells in response to alveolar injury and lung diseases.

Exploring cellular and molecular mechanisms controlling cell fate of lung progenitor cells in diseased conditions such as congenital pulmonary airway malformation using single cell and spatial transcriptomics.

Investigating saccular and alveolar stage development using non-human lung models and developing in vitro 3D alveoli structures comprised of alveolar type 1 and 2 cells with tissue engineering technology.